You take the motorway A8 Salzburg - Passau - Nürnberg to the three-leg motorway interchange Inntal, then the A93 in direction of Innsbruck to Kufstein. Leave at the second exit after the border, Kufstein South and follow the signs "Felbertauern". Then go via Kitzbühel, Pass Thurn, Mittersill and Felbertauern to Lienz.
Take the motorway A2 in direction of Graz and Klagenfurt as far as the motorway junction Villach and then the A10 in direction of Salzburg to Spittal/Drau. Continue on the road B100 to Lienz.